The Central Prairie League is a high school athletics conference comprising eleven high schools in Kansas. The schools compete in interscholastic athletic events such as football, basketball, softball, golf, and baseball.
| School | Mascot | Colors | Location |
|---|---|---|---|
| Central Plains | Oilers | Claflin, Kansas | |
| Kinsley | Coyotes | Kinsley, Kansas | |
| LaCrosse | Leopards | LaCrosse, Kansas | |
| Macksville | Mustangs | Macksville, Kansas | |
| Ness City | Eagles | Ness City, Kansas | |
| Otis-Bison | Cougars | Otis, Kansas | |
| St. John | Tigers | St. John, Kansas | |
| Victoria | Knights | Victoria, Kansas | |
| Western Plains | Bobcats | Ransom, Kansas |